It has been well accepted by mining researchers that coal tends to undergo abrupt fracture under the coupling effect of dynamic and static loads.Hence, the study of influence of coupled static and dynamic loads on coal failure behaviour is meaningful for the understanding of coal burst.In Sideboard this paper, PFC modelling of SHPB test is adopted
Relationship between type III secretion toxins, biofilm formation, and antibiotic resistance in clinical Pseudomonas aeruginosa isolates
Background and aim.Pseudomonas aeruginosa is considered as a notorious pathogen due to its multidrug resistance and life threatening infections.We investigated the relationship between type III secretion toxins, biofilm formation, and antibiotic resistance among clinical P.aeruginosa isolates.Methods.A total of 70 genetically distinct clinical P.ae
Analysis of Myc-induced histone modifications on target chromatin.
The c-myc proto-oncogene is induced by mitogens and is a central regulator of cell growth and differentiation.The c-myc product, Myc, is a transcription factor that binds a multitude of genomic sites, estimated to be over 10-15% of all promoter regions.Target promoters generally pre-exist in an active or poised chromatin state that is further modif
Disease burden of breast cancer and risk factors in Europe 44 countries, 1990-2019: findings of the global burden of disease study 2019
BackgroundBreast cancer (BC) represents a significant health challenge in Europe due to its elevated prevalence and heterogeneity.Despite notable progress in diagnostic and treatment methods, the region continues to grapple with rising BC burdens, with comprehensive investigations into this matter notably lacking.This study explores BC burden and p